Premium
Rhodium(III)‐Catalyzed Regioselective Decarboxylative Cyclization for the Synthesis of 4 H ‐Furo[3,2‐ c ]chromen‐4‐one Derivatives
Author(s) -
Zha Dandan,
Li Hongji,
Li Shiqing,
Wang Lei
Publication year - 2017
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201600974
Subject(s) - chemistry , hypervalent molecule , regioselectivity , decarboxylation , rhodium , catalysis , reagent , iodine , combinatorial chemistry , organic chemistry , medicinal chemistry
This contribution describes a regioselective cyclization of hypervalent iodine reagents (HIR) with propiolic acids in the presence of a rhodium catalyst. The mild decarboxylation can tolerate a wide range of groups and generates 4 H ‐furo[3,2‐ c ]chromen‐4‐one derivatives in good isolated yields.