Premium
Recent Advances in Multicomponent Synthesis of 1,4,5‐Trisubstituted 1,2,3‐Triazoles
Author(s) -
Chen Zhengkai,
Liu Zhubo,
Cao Gangjian,
Li Hongli,
Ren Hongjun
Publication year - 2017
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201600918
Subject(s) - chemistry , broad spectrum , combinatorial chemistry , nanotechnology , materials science
1,4,5‐Trisubstituted 1,2,3‐triazoles have been regarded as highly significant nitrogen‐containing heterocycles due to their broad spectrum of biological activities and other prominent properties. Well‐established pioneering examples indicate that multicomponent reactions (MCRs) are a straightforward and powerful tool for the construction of various functionalized heterocyclic molecules, especially fully‐decorated 1,2,3‐triazoles. The recent progress regarding synthetic approaches towards differently substituted types of 1,2,3‐triazoles via MCRs and the relevant mechanistic investigations is summarized in this review.