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Commercial Supported Gold Nanoparticles Catalyzed Alkyne Hydroamination and Indole Synthesis
Author(s) -
Liang Shengzong,
Hammond Luisa,
Xu Bo,
Hammond Gerald B.
Publication year - 2016
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201600804
Subject(s) - hydroamination , alkyne , chemistry , catalysis , intramolecular force , indole test , intermolecular force , nanoparticle , combinatorial chemistry , solvent , organic chemistry , nanotechnology , molecule , materials science
Commercial gold nanoparticles supported on titanium dioxide (TiO 2 ) were found to be a highly efficient catalyst for alkyne hydroamination. Terminal alkynes could easily undergo intermolecular hydroamination with low catalyst loadings (0.2 mol% Au) under solvent‐free conditions. Indoles were efficiently synthesized using microwave heating through intramolecular hydroamination.