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Stereocontrolled [4+1] Annulation of α‐Hydroxycyclobutenones: Synthesis of Polysubstituted Cyclopentenones
Author(s) -
Mao Xu,
Song Peidong,
Hao Yu,
Sun Zezhong,
Hu Xiangdong
Publication year - 2016
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201600670
Subject(s) - annulation , chemistry , stereoselectivity , diene , combinatorial chemistry , stereochemistry , organic chemistry , catalysis , natural rubber
A stereocontrolled [4+1] annulation of α‐hydroxycyclobutenones has been disclosed. For the first time, α‐hydroxycyclobutenones have been proven as facile diene precursors for [4+1] annulation. Meanwhile, the reported transformation presents a concise synthetic route to polysubstituted cyclopentenones with high stereoselectivity.
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