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Diverse Reactivity in a Rhodium(III)‐Catalyzed Vinylic sp 2 C–H Bond Functionalization: Synthesis of Fused Polycyclic Heteroarenes or Conjugated Dienes
Author(s) -
Li ShuaiShuai,
Xia YingQi,
Liu ChenFei,
Zhang GuoTai,
Su Fu,
Zhang XiaoMei,
Dong Lin
Publication year - 2016
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201600666
Subject(s) - chemistry , rhodium , reactivity (psychology) , conjugated system , surface modification , catalysis , diene , coupling reaction , medicinal chemistry , double bond , stereochemistry , combinatorial chemistry , polymer chemistry , organic chemistry , polymer , medicine , alternative medicine , pathology , natural rubber
An efficient rhodium(III)‐catalyzed vinylic sp 2 C–H bond activation of 7‐azaindoles with alkynes is reported, leading to the controlled synthesis of stereodefined diene and fused polycyclic heteroarene products. The novel strategy for the synthesis of diverse coupling products was controlled by the reaction conditions and the substitutions on the vinyl group.