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An Efficient Heterobimetallic Lanthanide Alkoxide Catalyst for Transamidation of Amides under Solvent‐Free Conditions
Author(s) -
Sheng Hongting,
Zeng Ruijie,
Wang Wenjuan,
Luo Shuwen,
Feng Yan,
Liu Jing,
Chen Weijian,
Zhu Manzhou,
Guo Qingxiang
Publication year - 2017
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201600373
Subject(s) - chemistry , lanthanide , bifunctional , catalysis , substrate (aquarium) , alkoxide , combinatorial chemistry , reactivity (psychology) , solvent , organic chemistry , primary (astronomy) , polymer chemistry , medicine , ion , oceanography , alternative medicine , physics , pathology , astronomy , geology
A practical heterobimetallic lanthanide‐catalyzed transamidation of primary, secondary and tertiary amides with aliphatic and aromatic amines has been developed. The methodology was also applied to the weakly reactive thioamides to demonstrate its versatility and wide substrate scope. The heterobimetallic lanthanide catalysts showed high catalytic activity and a wide scope of substrates with good to excellent yields under solvent‐free conditions. Efficient activation of the transamidation can be realized by the above complexes acting as cooperative acid–base bifunctional catalysts, which are proposed to be responsible for the higher reactivity in comparison with simple monometallic catalysts.