Mild and Direct Multiple Deuterium‐Labeling of Saturated Fatty Acids | Zendy

Yamada Tsuyoshi | Zendy; Park Kwihwan | Zendy; Yasukawa Naoki | Zendy; Morita Kosuke | Zendy; Monguchi Yasunari | Zendy; Sawama Yoshinari | Zendy; Sajiki Hironao | Zendy

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Mild and Direct Multiple Deuterium‐Labeling of Saturated Fatty Acids

Author(s) -

Yamada Tsuyoshi,

Park Kwihwan,

Yasukawa Naoki,

Morita Kosuke,

Monguchi Yasunari,

Sawama Yoshinari,

Sajiki Hironao

Publication year - 2016

Publication title -

advanced synthesis and catalysis

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.541

H-Index - 155

eISSN - 1615-4169

pISSN - 1615-4150

DOI - 10.1002/adsc.201600363

Subject(s) - chemistry , deuterium , isopropyl , isopropyl alcohol , solvent , hydrogen , fatty alcohol , alcohol , catalysis , organic chemistry , medicinal chemistry , quantum mechanics , physics

We have established a mild and direct platinum on carbon (Pt/C)‐catalyzed multi‐deuterium labeling of various saturated fatty acids including bioactive compounds with high deuterium efficiencies in a mixed solvent of isopropyl alcohol and deuterium oxide ( i‐ PrOH)/D 2 O under neutral conditions at 120 °C without the external addition of deuterium or hydrogen gas.

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