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Acylperoxycoumarins as ortho ‐CH Acylating Agent via a Palladium(II)‐Catalyzed Redox‐Neutral Process
Author(s) -
Ranjan Mohanta Prakash,
Banerjee Arghya,
Kumar Santra Sourav,
Behera Ahalya,
Patel Bhisma K.
Publication year - 2016
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201600258
Subject(s) - chemistry , acylation , palladium , redox , catalysis , acyl group , combinatorial chemistry , medicinal chemistry , organic chemistry , group (periodic table)
An unprecedented palladium(II)‐catalyzed biomimetic aliphatic acyl (‐COR) group transfer was observed from acyl‐α‐peroxycoumarins to the ortho CH sites of directing arenes. Here, the CH activation is associated with a concomitant acyl group transfer via a Pd(II)‐catalyzed, redox‐neutral process. While methods for ortho aroylation (‐COAr) are well documented ortho acylation (‐COR) processes are scarce, hence the present redox‐neutral method is most ideal for o ‐acylation of directing substrates.