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Electron‐Poor, Fluoro‐Containing Arylboronic Acids as Efficient Coupling Partners for Bis(1,5‐cyclooctadiene)nickel(0)/Tricyclohexylphosphine‐Catalyzed Cross‐Coupling Reactions of Aryl Arenesulfonates
Author(s) -
Chen WenBo,
Xing ChunHui,
Dong Jie,
Hu QiaoSheng
Publication year - 2016
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201600205
Subject(s) - tricyclohexylphosphine , chemistry , nickel , catalysis , aryl , bromide , medicinal chemistry , 1,5 cyclooctadiene , organic chemistry , phosphine , alkyl
The use of electron‐poor, fluoro‐containing arylboronic acids as general coupling partners for nickel(0)/tricyclohexylphosphine‐catalyzed cross‐coupling of aryl arenesulfonates is described. Electron‐poor fluoro‐containing arylboronic acids were found to react faster than electron‐rich/neutral arylboronic acids, with (4‐methoxyphenyl)(4‐methylbenzenesulfonato‐κ O )bis(tricyclohexylphosphine)nickel. Bis(1,5‐cyclooctadiene)nickel(0)/tricyclohexylphosphine, (4‐methoxyphenyl)(4‐methylbenzenesulfonato‐κ O )bis(tricyclohexylphosphine)nickel and bis(tricyclohexylphosphine)nickel(II) bromide were all found to be efficient catalysts/catalyst precursors.