Premium
Nickel(II)‐Mediated Regioselective CH Monoiodination of Arenes and Heteroarenes by using Molecular Iodine
Author(s) -
Khan Bhuttu,
Kant Ruchir,
Koley Dipankar
Publication year - 2016
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201600177
Subject(s) - regioselectivity , chemistry , iodine , nickel , halogenation , organic chemistry , combinatorial chemistry , catalysis
The 8‐aminoquinoline‐directed, nickel(II)‐mediated ortho ‐iodination of benzamides using molecular iodine has been developed. The process is highly regioselective and furnishes only monoiodinated products. A broad range of arenes and heteroarenes with diverse functional groups provided monoiodinated products in good to excellent yields.