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Rhodium‐Catalyzed Tandem Annulation Reactions of 7‐Azaindoles with Electron‐Deficient Olefins via Double CH Activation
Author(s) -
Li ShuaiShuai,
Lin Hui,
Liu ChenFei,
Xia YingQi,
Zhang XiaoMei,
Dong Lin
Publication year - 2016
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201600112
Subject(s) - chemistry , annulation , rhodium , tandem , intramolecular force , catalysis , alkylation , quaternary carbon , medicinal chemistry , double bond , olefin fiber , combinatorial chemistry , stereochemistry , organic chemistry , enantioselective synthesis , materials science , composite material
Rhodium‐catalyzed tandem annulation reactions via olefination and subsequent intramolecular C‐Michael‐type cyclization represent an efficient approach for the direct construction of CC bonds. The simple and atom‐economic strategy produces various alkylation derivatives of 7‐azaindole with a quaternary carbon center from 7‐azaindoles and olefins.