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Metal‐Free Oxidative Decarbonylative Hydroalkylation of Alkynes with Secondary and Tertiary Alkyl Aldehydes
Author(s) -
Ouyang XuanHui,
Song RenJie,
Liu Bang,
Li JinHeng
Publication year - 2016
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201501113
Subject(s) - chemistry , decarbonylation , alkyl , protonation , peroxide , organic chemistry , medicinal chemistry , catalysis , ion
A new, metal‐free, radical‐mediated oxidative decarbonylative hydroalkylation of various alkynes with secondary and tertiary alkyl aldehydes using di‐ tert ‐butyl peroxide (DTBP) as oxidant is presented. This method enables the simultaneous formation of a CC bond and a CH bond through a sequence of decarbonylation, radical addition and protonation, and provides a straightforward route for transforming alkynes into alkenes with high compatibility with both alkynes and alkyl aldehydes.