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Organophotocatalytic Synthesis of Phosphoramidates
Author(s) -
Meazza Marta,
Kowalczuk Agnieszka,
Shirley Luke,
Yang Jung Woon,
Guo Hao,
Rios Ramon
Publication year - 2016
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201501068
Subject(s) - chemistry , rendering (computer graphics) , catalysis , organic synthesis , green chemistry , organic chemistry , combinatorial chemistry , organic base , coupling reaction , reaction mechanism , computer graphics (images) , computer science
Abstract We describe the use of visible light in conjunction with an organic dye for the synthesis of phosphoramidates. Cross dehydrogenative coupling reactions between phosphites and amines are reported using organic dyes and light as catalysts for the first time. It is not only a novel application of organic dyes but also fulfils the requirement of sustainability and green chemistry avoiding the use of chromatographic purification techniques. The product was simply isolated from the reaction mixture via an acid‐base work‐up procedure, rendering the pure product in good yields.