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Nickel‐Catalyzed α‐Benzylation of Arylacetonitriles via CO Activation
Author(s) -
Xiao Jing,
Yang Jia,
Chen Tieqiao,
Han LiBiao
Publication year - 2016
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201500822
Subject(s) - chemistry , catalysis , nickel , alcohol , reaction conditions , medicinal chemistry , combinatorial chemistry , organic chemistry
Abstract Efficient Ni‐catalyzed direct cross‐couplings of benzylic alcohol derivatives with arylacetonitriles via CO activation are described. Various α‐benzylated arylacetonitriles including those with functional groups can be prepared under mild reaction conditions.