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Iron‐Catalyzed Regioselective Oxo‐ and Hydroxy‐Phthalimidation of Styrenes: Access to α‐Hydroxyphthalimide Ketones
Author(s) -
Zhang Jizong,
Tang Yu
Publication year - 2016
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201500732
Subject(s) - chemistry , regioselectivity , catalysis , chloride , oxidative phosphorylation , medicinal chemistry , oxidation process , organic chemistry , combinatorial chemistry , chemical engineering , biochemistry , engineering
This paper describes the aerobic oxidation of styrenes catalyzed by iron(III) chloride (FeCl 3 ) to form β‐keto‐ N ‐alkoxyphthalimides in fair to good yields. This oxidative process employs mild conditions with green and atom efficient dioxygen (O 2 ) as the oxidant.
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