Premium
Water‐Soluble Gold–N‐Heterocyclic Carbene Complexes for the Catalytic Homogeneous Acid‐ and Silver‐Free Hydration of Hydrophilic Alkynes
Author(s) -
Ibrahim Houssein,
de Frémont Pierre,
Braunstein Pierre,
Théry Vincent,
Nauton Lionel,
Cisnetti Federico,
Gautier Arnaud
Publication year - 2015
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201500729
Subject(s) - chemistry , carbene , catalysis , halide , homogeneous , combinatorial chemistry , water soluble , homogeneous catalysis , organic chemistry , polymer chemistry , photochemistry , physics , thermodynamics
Water‐soluble gold(III/I) N‐heterocylic carbene complexes behave as efficient catalysts for the hydration of terminal alkynes in neat water. The transformation proceeds in the absence of Brønsted acids or halide scavengers and is suitable for sensitive substrates. Kinetic profiles and DFT studies provide a clear picture of intermediates present during catalysis.