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Iridium‐ and Rhodium‐Catalyzed Carbocyclization between 2‐Phenylimidazo[1,2‐ a ]pyridine and α‐Diazo Esters
Author(s) -
Li Yunyun,
Wang Fen,
Yu Songjie,
Li Xingwei
Publication year - 2016
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201500709
Subject(s) - iridium , rhodium , chemistry , diazo , pyridine , intramolecular force , catalysis , medicinal chemistry , nucleophile , combinatorial chemistry , stereochemistry , organic chemistry
Iridium(III) and rhodium(III) complexes can catalyze the carbocyclization between 2‐phenylimidazo[1,2‐ a ]pyridine and α‐diazo esters. The reaction occurs via CH activation and dialkylation of the arene followed by intramolecular nucleophilic substitution. Iridium(III) and rhodium(III) catalysis offer complementary scopes with respect to the α‐diazo esters.