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Synthesis of 3‐Arylpyridines via Palladium/Copper‐Catalyzed Annulation of Allylamine/1,3‐Propanediamine and Aldehydes
Author(s) -
Yang Xiaodong,
Yang Shenghua,
Xiang Likui,
Pang Xiaobo,
Chen Baohua,
Huang Guosheng,
Yan Rulong
Publication year - 2015
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201500685
Subject(s) - allylamine , chemistry , annulation , palladium , catalysis , tandem , copper , medicinal chemistry , combinatorial chemistry , organic chemistry , polymer , materials science , polyelectrolyte , composite material
A novel and efficient method for the synthesis of 3‐arylpyridines from allylamine/propanediamine and aldehydes by palladium/copper‐catalyzed oxidative tandem cyclization has been developed. With this reaction, a series of desired 3‐arylpyridines was synthesized in moderate yields via CC/CN bond formation and 6‐ endo/exo‐trig cyclization.