Synthesis of 3‐Arylpyridines  via  Palladium/Copper‐Catalyzed Annulation of Allylamine/1,3‐Propanediamine and Aldehydes | Zendy

Yang Xiaodong | Zendy; Yang Shenghua | Zendy; Xiang Likui | Zendy; Pang Xiaobo | Zendy; Chen Baohua | Zendy; Huang Guosheng | Zendy; Yan Rulong | Zendy

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Synthesis of 3‐Arylpyridines via Palladium/Copper‐Catalyzed Annulation of Allylamine/1,3‐Propanediamine and Aldehydes

Author(s) -

Yang Xiaodong,

Yang Shenghua,

Xiang Likui,

Pang Xiaobo,

Chen Baohua,

Huang Guosheng,

Yan Rulong

Publication year - 2015

Publication title -

advanced synthesis and catalysis

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.541

H-Index - 155

eISSN - 1615-4169

pISSN - 1615-4150

DOI - 10.1002/adsc.201500685

Subject(s) - allylamine , chemistry , annulation , palladium , catalysis , tandem , copper , medicinal chemistry , combinatorial chemistry , organic chemistry , polymer , materials science , polyelectrolyte , composite material

A novel and efficient method for the synthesis of 3‐arylpyridines from allylamine/propanediamine and aldehydes by palladium/copper‐catalyzed oxidative tandem cyclization has been developed. With this reaction, a series of desired 3‐arylpyridines was synthesized in moderate yields via CC/CN bond formation and 6‐ endo/exo‐trig cyclization.

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