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Stable and Reusable Binaphthyl‐Supported Palladium Catalyst for Aminocarbonylation of Aryl Iodides
Author(s) -
Sharma Nidhi,
Sekar Govindasamy
Publication year - 2016
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201500642
Subject(s) - chemistry , aryl , catalysis , palladium , carbon monoxide , carbonylation , organic chemistry , combinatorial chemistry , alkyl
A binaphthyl‐supported Pd nanoparticles (Pd‐BNP)‐catalyzed aminocarbonylation of aryl iodides in the presence of carbon monoxide and amines for the synthesis of amides has been developed. This methodology provides an efficient route for the synthesis of a COX‐2 enzyme inhibitor having anti‐inflammatory activity.