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Zinc Acetate‐Catalyzed Enantioselective Hydrosilylation of Ketones
Author(s) -
Szewczyk Marcin,
Stanek Filip,
Bezłada Agata,
Mlynarski Jacek
Publication year - 2015
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201500583
Subject(s) - chemistry , hydrosilylation , enantioselective synthesis , zinc , catalysis , organic chemistry , ligand (biochemistry) , salt (chemistry) , aryl , combinatorial chemistry , receptor , alkyl , biochemistry
Zinc acetate complexes with a chiral diphenylethylenediamine (DPEDA)‐derived ligand have been proved to be efficient catalysts for the enantioselective hydrosilylation of aryl ketones. Replacing pyrophoric dialkylzinc with the readily available zinc salt simplifies the procedures and provides excellent conversions (up to >99%) and enantioselectivities ( ee s up to 97%).