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Stannylation and Stille Coupling of Base‐Sensitive Tetrahydroxanthones to Heteromeric Biaryls
Author(s) -
Lindner Stephanie,
Nieger Martin,
Bräse Stefan
Publication year - 2015
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201500524
Subject(s) - stille reaction , chemistry , benzene , coupling (piping) , base (topology) , combinatorial chemistry , core (optical fiber) , stereochemistry , organic chemistry , polymer , computer science , mathematical analysis , mechanical engineering , telecommunications , mathematics , engineering
Herein, the synthesis of heteromeric tetrahydroxanthone biaryls is described, a widespread core structure of many natural products. The development of both stannylation and Stille coupling procedures of base‐sensitive tetrahydroxanthones enabled their coupling with benzene derivatives as well as with xanthenes. These methods provide access to structures that are analogous to parnafungins as well as to dimeric compounds similar to secalonic acids or phomoxanthones.