Copper‐Catalyzed Aerobic Oxidative C(aryl)OH Bond Functionalization of Catechols with Amines Affording Benzoxazoles | Zendy

Chen Xiuling | Zendy; Ji Fangyan | Zendy; Zhao Yalei | Zendy; Liu Yanxi | Zendy; Zhou Yongbo | Zendy; Chen Tieqiao | Zendy; Yin ShuangFeng | Zendy

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Copper‐Catalyzed Aerobic Oxidative C(aryl)OH Bond Functionalization of Catechols with Amines Affording Benzoxazoles

Author(s) -

Chen Xiuling,

Ji Fangyan,

Zhao Yalei,

Liu Yanxi,

Zhou Yongbo,

Chen Tieqiao,

Yin ShuangFeng

Publication year - 2015

Publication title -

advanced synthesis and catalysis

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.541

H-Index - 155

eISSN - 1615-4169

pISSN - 1615-4150

DOI - 10.1002/adsc.201500515

Subject(s) - chemistry , catechol , catalysis , surface modification , aryl , amine gas treating , copper , oxidative phosphorylation , organic chemistry , combinatorial chemistry , polymer chemistry , biochemistry , alkyl

The first copper‐catalyzed aerobic oxidative C(aryl)OH bond functionalization of catechols is reported. Under air, at room temperature, in the presence of a copper catalyst, catechols react with amines to produce the corresponding benzoxazoles in high yields. Mechanistic studies suggest that the reaction proceeds via an intriguing competitive oxidation and a synergetic catalysis between catechol and amine.

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