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Nickel‐Catalyzed Synthesis of Enamides and Enecarbamates via Isomerization of Allylamides and Allylcarbamates
Author(s) -
Halli Juliette,
Kramer Philipp,
Bechthold Maren,
Manolikakes Georg
Publication year - 2015
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201500461
Subject(s) - isomerization , chemistry , nickel , catalysis , scope (computer science) , combinatorial chemistry , component (thermodynamics) , scale (ratio) , organic chemistry , physics , quantum mechanics , computer science , thermodynamics , programming language
A single‐component, air‐stable nickel precatalyst can catalyze the isomerization of allylamides for the synthesis of enamides. The scope of the reaction encompasses various substituted allylamides and allylcarbamates as well as homoallylamides. The reaction can be performed on a multigram‐scale without specialized glove‐box equipment or Schlenk techniques.