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Enantioselective Palladium‐Catalyzed Heck–Heck Cascade Reactions: Ready Access to the Tetracyclic Core of Lycorane Alkaloids
Author(s) -
Coya Estibaliz,
Sotomayor Nuria,
Lete Esther
Publication year - 2015
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201500431
Subject(s) - chemistry , heck reaction , enantioselective synthesis , palladium , catalysis , cascade , binap , organic chemistry , combinatorial chemistry , chromatography
A rapid and efficient access to a wide variety of enantiomerically enriched C‐11b substituted lycorane analogues can be achieved via a catalytic asymmetric Heck–Heck 6‐ exo /6‐ endo cascade reaction in the presence of ( R )‐BINAP.
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