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A One‐Pot Approach to Phenanthridine Derivatives through Two‐Step Rhodium(I) and Gold(I) Catalysis
Author(s) -
Zhu Zizhong,
Chen Kai,
Xu Qin,
Shi Min
Publication year - 2015
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201500407
Subject(s) - phenanthridine , chemistry , rhodium , cycloaddition , catalysis , combinatorial chemistry , substrate (aquarium) , scope (computer science) , organic chemistry , computer science , programming language , oceanography , geology
Abstract An effective one‐pot procedure for the synthesis of phenanthridine derivatives containing N‐ or O‐heterocycles has been developed through a two‐step rhodium‐catalyzed [2+2+2] cycloaddition and gold‐catalyzed heterocyclization under mild conditions. The substrate scope has been investigated and a plausible reaction mechanism has been proposed on the basis of control experiments and previous literature reports.