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Nitrative Cyclization of 1‐Ethynyl‐2‐(vinyloxy)benzenes to Access 1‐[2‐(Nitromethyl)benzofuran‐3‐yl] Ketones Through Dioxygen Activation
Author(s) -
Hu Ming,
Liu Bang,
Ouyang XuanHui,
Song RenJie,
Li JinHeng
Publication year - 2015
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201500336
Subject(s) - chemistry , benzofuran , medicinal chemistry , oxygen , triple bond , carbon atom , protonation , oxygen atom , photochemistry , polymer chemistry , organic chemistry , double bond , molecule , ring (chemistry) , ion
A new metal‐free method for the nitrative cyclization of 1‐ethynyl‐2‐(vinyloxy)benzenes with tert ‐butyl nitrite ( t‐ BuONO), air and water at room temperature is presented, in which an oxygen atom is introduced into the carbon‐carbon triple bond to form a new carbonyl group through dioxygen activation.