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Recent Advances of α‐Isothiocyanato Compounds in the Catalytic Asymmetric Reaction
Author(s) -
Han WenYong,
Zhao JianQiang,
Zuo Jian,
Xu XiaoYing,
Zhang XiaoMei,
Yuan WeiCheng
Publication year - 2015
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201500264
Subject(s) - chemistry , reagent , enantioselective synthesis , catalysis , aldol reaction , organic chemistry , combinatorial chemistry , cascade , mannich reaction , chromatography
α‐Isothiocyanato amides, esters and phosphonates have emerged as new types of versatile reagents for various organo‐ and metal‐catalyzed asymmetric cascade reactions, which have attracted increasing interest of many chemists. In this review, recent advances of α‐isothiocyanato compounds for the asymmetric cascade aldol/cyclization, Mannich/cyclization, Michael/cyclization, diverse [3+2] cyclization, and self‐cyclization/addition reactions are summarized and classified according to the types of acceptors.