3‐Naphthylindole Construction by Rhodium(II)‐Catalyzed Regioselective Direct Arylation of Indoles with 1‐Diazonaphthalen‐2‐(1 H )‐ones | Zendy

Baral Ek Raj | Zendy; Lee Yong Rok | Zendy; Kim Sung Hong | Zendy

Premium

3‐Naphthylindole Construction by Rhodium(II)‐Catalyzed Regioselective Direct Arylation of Indoles with 1‐Diazonaphthalen‐2‐(1 H )‐ones

Author(s) -

Baral Ek Raj,

Lee Yong Rok,

Kim Sung Hong

Publication year - 2015

Publication title -

advanced synthesis and catalysis

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.541

H-Index - 155

eISSN - 1615-4169

pISSN - 1615-4150

DOI - 10.1002/adsc.201500209

Subject(s) - regioselectivity , chemistry , rhodium , benzofuran , pyrrole , catalysis , yield (engineering) , furan , medicinal chemistry , combinatorial chemistry , organic chemistry , materials science , metallurgy

The regioselective direct 3‐arylation of indoles with 1‐diazonaphthalen‐2‐(1 H )‐ones was developed by means of a rhodium(II) pivalate‐catalyzed cross‐coupling reaction. This procedure provided a variety of novel 3‐naphthylindoles in high yield. The direct coupling of benzofuran, pyrrole or furan with 1‐diazonaphthalen‐2‐(1 H )‐ones afforded 2‐ or 3‐naphthyl substituted heterocycles.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research