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Inside Cover: CN Coupling of Indoles and Carbazoles with Aromatic Chlorides Catalyzed by a Single‐Component NHC‐Nickel(0) Precursor (Adv. Synth. Catal. 5/2015)
Author(s) -
Rull Silvia G.,
Blandez Juan F.,
Fructos Manuel R.,
Belderrain Tomás R.,
Nicasio M. Carmen
Publication year - 2015
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201500196
Subject(s) - chemistry , nickel , catalysis , halide , aryl , styrene , carbene , ligand (biochemistry) , medicinal chemistry , combinatorial chemistry , organic chemistry , polymer chemistry , copolymer , alkyl , biochemistry , receptor , polymer
The inside cover picture , provided by T. R. Belderrain, M. C. Nicasio and co‐workers, illustrates the first example of nickel‐mediated N ‐(hetero)arylation of indoles and carbazoles with (hetero)aromatic chlorides, the least expensive of aryl halides. The reported procedure, based on the use of the Ni(0) complex [(IPr)Ni(styrene) 2 ] as catalytic precursor, affords the products in good to high yields, in short reac tion times without the addition of an excess of the N‐heterocycle carbene ligand. Details can be found in the communication on pages 907–911 (S. G. Rull, J. F. Blandez, M. R. Fructos, T. R. Belderrain, M. C. Nicasio, Adv. Synth. Catal. 2015, 357, 907–911; DOI: 10.1002/adsc.201500030 ).