Premium
N,N′ ‐Dioxide/Zinc Bis(trifluoromethylsulfonyl)imide Complex Catalyzed Enantioselective Diels–Alder Reaction of Cyclopentadiene with Alkynones
Author(s) -
Kang Tengfei,
Wang Zhen,
Lin Lili,
Liao Yuting,
Zhou Yuhang,
Liu Xiaohua,
Feng Xiaoming
Publication year - 2015
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201500069
Subject(s) - cyclopentadiene , chemistry , enantioselective synthesis , imide , diels–alder reaction , zinc , catalysis , organic chemistry , enantiomer , enantiomeric excess , medicinal chemistry
An N,N′ ‐dioxide/zinc bis(trifluoromethylsulfonyl)imide complex has been developed as an efficient catalyst for the highly enantioselective Diels–Alder reaction of cyclopentadiene with alkynones. Various 2‐acyl substituted norbornadiene derivatives were obtained in moderate to high yields (up to 99 %) with good enantiomeric excesses (up to 95 %).