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Novel DNA Catalysts Based on G‐Quadruplex for Organic Synthesis
Author(s) -
Wang LiXia,
Xiang JunFeng,
Tang YaLin
Publication year - 2015
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201400818
Subject(s) - chemistry , stacking , catalysis , g quadruplex , dna , combinatorial chemistry , molecule , organic molecules , small molecule , function (biology) , molecular recognition , nanotechnology , stereochemistry , organic chemistry , biochemistry , biology , materials science , evolutionary biology
Double‐stranded DNA (dsDNA) as a catalytic species has been applied in various key asymmetric reactions. Compared with dsDNA, G‐quadruplex DNAs (G4DNAs) have unique conformational structures and versatile complexation properties, and act expectedly as hosts to recognize planar aromatic molecules through π–π stacking. Based on the specific recognition for small molecules, G4DNA‐based catalysts have been used to assist the catalytic function, and have been applied in asymmetric organic reactions.