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Silver(I)‐Mediated CH Amination of 2‐Alkenylanilines: Unique Solvent‐Dependent Migratory Aptitude
Author(s) -
Youn So Won,
Ko Tae Yun,
Jang Min Jung,
Jang Su San
Publication year - 2015
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201400759
Subject(s) - chemistry , amination , substrate (aquarium) , solvent , functional group , combinatorial chemistry , organic chemistry , catalysis , oceanography , polymer , geology
A highly effective silver(I)‐mediated CH amination of 2‐alkenylanilines has been developed to afford a diverse range of substituted indoles. High functional group tolerance, broad substrate scope, simple/fast/high‐yielding reaction, and recovery/reuse of the inexpensive silver oxidant are noteworthy. Furthermore, an uncommon migratory process of β‐monosubstituted 2‐alkenylanilines with solvent‐dependence was demonstrated.