Oxidative Alkenylation/Annulation of Benzimidates  via  Ruthenium(II)‐Catalyzed CH Activation to Generate 3‐Methyleneisoindolin‐1‐ones | Zendy

Li Xing Guang | Zendy; Sun Min | Zendy; Liu Kai | Zendy; Liu Pei Nian | Zendy

Premium

Oxidative Alkenylation/Annulation of Benzimidates via Ruthenium(II)‐Catalyzed CH Activation to Generate 3‐Methyleneisoindolin‐1‐ones

Author(s) -

Li Xing Guang,

Sun Min,

Liu Kai,

Liu Pei Nian

Publication year - 2015

Publication title -

advanced synthesis and catalysis

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.541

H-Index - 155

eISSN - 1615-4169

pISSN - 1615-4150

DOI - 10.1002/adsc.201400727

Subject(s) - annulation , ruthenium , chemistry , catalysis , stereoselectivity , cascade , oxidative phosphorylation , combinatorial chemistry , stereochemistry , medicinal chemistry , organic chemistry , biochemistry , chromatography

A novel ruthenium‐catalyzed oxidative alkenylation/annulation cascade reaction is described for synthesizing 3‐methyleneisoindolin‐1‐ones. In the protocol, the N H imidate is applied efficiently as a directing group in ruthenium‐catalyzed CH activation, generating various 3‐methyleneisoindolin‐1‐ones with high regio‐ and stereoselectivity in moderate to good yields.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research