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Lewis Acid‐Catalyzed Electrophilic Trifluoromethylthiolation of (Hetero)Arenes
Author(s) -
Wang Qiang,
Qi Zisong,
Xie Fang,
Li Xingwei
Publication year - 2015
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201400717
Subject(s) - chemistry , electrophile , catalysis , reagent , lewis acids and bases , organic chemistry , medicinal chemistry , combinatorial chemistry
( N ‐Trifluoromethylthio)saccharin has been applied as an electrophilic trifluoromethylthiolating reagent for a broad scope of heteroarenes, electron‐donating group (EDG)‐activated benzenes, and several electron‐rich olefins. Iron(III) and gold(III) catalysts showed complementary activity for different substrates.