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Cover Picture: Deracemization of Amino Acids by Coupling Transaminases of Opposite Stereoselectivity (Adv. Synth. Catal. 17/2014)
Author(s) -
Park EulSoo,
Shin JongShik
Publication year - 2014
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201400600
Subject(s) - stereoselectivity , enantiopure drug , chemistry , oxidase test , coupling (piping) , amino acid , stereochemistry , enantioselective synthesis , organic chemistry , biochemistry , enzyme , catalysis , mechanical engineering , engineering
The front cover picture , provided by Eul‐Soo Park and Jong‐Shik Shin, illustrates deracemization of amino acids by coupling transaminases of opposite stereoselectivity. The authors demonstrated that racemic amino acids could be converted into both enantiopure forms, depending on the stereoselectivity of the transaminases. Moreover, this strategy is free of H 2 O 2 generation which is troublesome in oxidase‐based methods. Details can be found in the communication on pages 3505–3509 (E.‐S. Park, J.‐S. Shin, Adv. Synth. Catal. 2014, 356, 3505–3509; DOI: 10.1002/adsc.201400185) .