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Inside Cover Picture: Laccase/2,2,6,6‐Tetramethylpiperidinoxyl Radical (TEMPO): An Efficient Catalytic System for Selective Oxidations of Primary Hydroxy and Amino Groups in Aqueous and Biphasic Media (Adv. Synth. Catal. 10/2014)
Author(s) -
DíazRodríguez Alba,
MartínezMontero Lía,
Lavandera Iván,
Gotor Vicente,
GotorFernández Vicente
Publication year - 2014
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201400589
Subject(s) - chemistry , laccase , catalysis , ether , organic chemistry , aqueous solution , aqueous medium , enzyme
The inside cover picture, provided by Dbaz‐Rodrbguez et al., illustrates the oxidization of alcohols, diols or amino alcohols in buffer solution under aerobic conditions using the laccase from Trametes versicolor together with 2,2,6,6‐tetramethylpiperidinoxyl radical (TEMPO). This practical and efficient methodology promotes the chemoselective oxidation of hydroxy or amino groups, leading to aldehydes, lactones, hemiaminals or lactams in good yields. Addition of methyl tert‐butyl ether allows the TEMPO loading to be reduced, also enhancing the solubility of hydrophobic compounds. Details of this work can be found in the Update on pages 2321–2329 (A. Dbaz‐Rodrbguez, L. Martbnez‐Montero, I. Lavandera, V. Gotor, V. Gotor‐ Fernndez, Adv. Synth. Catal. 2014, 356, 2321–2329; DOI: 10.1002/adsc.201400260) .