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Cover Picture: Nickel‐Catalyzed Regio‐ and Stereoselective Reductive Coupling of Oxa‐ and Azabicyclic Alkenes with Enones and Electron‐Rich Alkynes (Adv. Synth. Catal. 10/2014)
Author(s) -
Mannathan Subramaniyan,
Cheng ChienHong
Publication year - 2014
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201400535
Subject(s) - chemistry , stereoselectivity , alkyl , catalysis , medicinal chemistry , nickel , reductive elimination , alkylation , stereochemistry , organic chemistry
The front cover picture, provided by Chien‐Hong Cheng, illustrates a highly regio‐ and stereoselective nickel‐catalyzed reductive coupling reaction of oxa‐ and azabicyclic alkenes with enones and electron‐rich alkynes. The reaction is highly atom economical affording cis‐2‐ alkyl‐ and alkenyl‐1,2‐dihydronaphthalenes in good to excellent yields. Besides, 2‐alkyl naphthalene derivatives also can be prepared under similar reaction conditions. The picture at the center is Department of Chemistry, National Tsing Hua University, in Hsinchu, Taiwan. Details can be found in the full paper on pages 2239–2246 (S. Mannathan and C.‐H. Cheng, Adv. Synth. Catal. 2014, 356, 2239–2246 DOI: 10.1002/adsc.201300910) .