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Copper‐Catalyzed Regioselective Oxytrifluoromethylation of Allenes Using a CF 3 ‐Transfer Reagent
Author(s) -
Wang Yanan,
Jiang Min,
Liu JinTao
Publication year - 2014
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201400320
Subject(s) - chemistry , reagent , regioselectivity , catalysis , copper , combinatorial chemistry , organic chemistry
A mild and efficient copper‐catalyzed oxytrifluoromethylation of allenes is demonstrated. The reaction tolerates a range of substrates to give a series of trifluoromethylated derivatives in moderate to good yields. Two possible pathways were proposed based on the reaction results and control experiments.