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Synthesis of 5‐(Fluoromethyl)‐4,5‐dihydroisoxazoles by Silver‐ Catalyzed Oxyfluorination of Unactivated Alkenes
Author(s) -
Liu YanYun,
Yang Ji,
Song RenJie,
Li JinHeng
Publication year - 2014
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201400242
Subject(s) - selectfluor , chemistry , alkene , catalysis , heteroatom , fluorine , organic chemistry , combinatorial chemistry , ring (chemistry)
A new silver‐catalyzed oxyfluorination of unactivated alkenes using commercially available Selectfluor as the fluorine source is presented. This method provides a new access to 5‐(fluoromethyl)‐4,5‐dihydroisoxazoles, and represents a new example of alkene 1,2‐difunctionalization by simultaneously forming two new carbon‐heteroatom bonds.