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Palladium‐Catalyzed CP Cross‐Coupling of Arylhydrazines with H‐Phosphonates via CN Bond Cleavage
Author(s) -
Xu Wentao,
Hu Gaobo,
Xu Pengxiang,
Gao Yuxing,
Yin Yingwu,
Zhao Yufen
Publication year - 2014
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201400155
Subject(s) - chemistry , palladium , bond cleavage , catalysis , aryl , cleavage (geology) , substrate (aquarium) , combinatorial chemistry , transition metal , oxygen , photochemistry , organic chemistry , alkyl , oceanography , geotechnical engineering , fracture (geology) , engineering , geology
A novel and efficient methodology that allows for the construction of CP bonds via the palladium‐catalyzed oxygen‐based oxidative cross‐coupling of various arylhydrazines with H‐phosphonates leading to valuable arylphosphonates has been developed with the use of O 2 as the green oxidant; the method has broad substrate applicability and furnishes good to excellent yields. This protocol is the first example of a transition metal‐catalyzed CP bond formation between arylhydrazines and H‐phosphonates via unactivated aryl CN bond cleavage.