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Visible Light Photoredox Catalysis: Investigation of Distal sp 3 CH Functionalization of Tertiary Amines for Alkylation Reaction
Author(s) -
Pandey Ganesh,
Jadhav Deepak,
Tiwari Sandip Kumar,
Singh Bhawana
Publication year - 2014
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201400107
Subject(s) - alkylation , chemistry , photoredox catalysis , alkyl , catalysis , surface modification , visible spectrum , photochemistry , medicinal chemistry , organic chemistry , photocatalysis , physics , optoelectronics
Abstract Visible light‐mediated photoredox activation of 10‐methyl‐9,10‐dihydroacridine in the presence of electron‐deficient alkenes leads to selective γ‐ sp 3 CH alkylation whereby 4‐alkyl‐ N,N‐ dimethylanilines produce substituted tetrahydroquinolines by a subsequent alkylation/cyclization sequence involving interesting mechanistic pathways.