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Inside Cover Picture: (Adv. Synth. Catal. 8/2013)
Publication year - 2013
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201390017
Subject(s) - iridium , chemistry , enantioselective synthesis , asymmetric hydrogenation , hydride , front cover , cationic polymerization , catalysis , ligand (biochemistry) , medicinal chemistry , stereochemistry , polymer chemistry , organic chemistry , cover (algebra) , metal , mechanical engineering , biochemistry , receptor , engineering
The inside front cover picture, provided by Carl A. Busacca and co‐workers, depicts an energy‐minimized iridium hydride complex of BIPI 238 with the dimethylindene substrate bound in the lower right quadrant. Cationic iridium catalysts containing BIPI ligands with a naphthyl core have been developed as highly enantioselective asymmetric hydrogenation catalysts. The naphthyl peri position has been identified as a critical stereocontrol element in the hydrogenation of tetrasubstituted, unfunctionalized olefins. It is believed to act by restricting the available conformations of the dicyclohexylphosphine group. The peri ‐fluoro ligand BIPI 238 is one of the most selective ligands found, as shown in the communication by Busacca and co‐workers on pages 1455–1463 (DOI: 10.1002/adsc.201201104).