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Tetrabutylammonium Iodide‐Catalyzed Radical Alkoxycarbonylation of 2‐Isocyanobiphenyls with Carbazates: Synthesis of Phenanthridine‐6‐carboxylates
Author(s) -
Li Xiaoqing,
Fang Mingwu,
Hu Peizhu,
Hong Guo,
Tang Yucai,
Xu Xiangsheng
Publication year - 2014
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201301158
Subject(s) - phenanthridine , chemistry , radical , catalysis , iodide , iodine , organic chemistry , methyl iodide , medicinal chemistry
A practical and environmentally friendly strategy for generating alkoxycarbonyl radicals from readily available carbazates under metal‐free conditions has been developed. In the presence of tetrabutylammonium iodide and tert ‐butyl hydroperoxide, 2‐isocyanobiphenyls smoothly underwent radical alkoxycarbonylation with carbazates to afford phenanthridine‐6‐carboxylates.