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Copper(I) Bromide‐Catalyzed Carbonylative Coupling of Aryl Halides with Phenols, Alcohols and Amines using Sodium Cyanide as C 1 Source: A Synthesis of Carboxylic Acid Derivatives
Author(s) -
Prasad Pragati K,
Sudalai Arumugam
Publication year - 2014
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201301155
Subject(s) - chemistry , aryl , bromide , cyanide , catalysis , carbonylation , sodium cyanide , carbon monoxide , phenols , halide , copper , organic chemistry , carboxylic acid , carboxylate , intramolecular force , alkyl
A new “carbon monoxide‐free” synthesis of carboxylate derivatives via carbonylative coupling of aryl bromides with phenols, alcohols, amines and acids in the presence of copper(I) bromide as catalyst and sodium cyanide in a stoichiometric amount has been developed. Its intramolecular version provides for the preparation of lactones (e.g., isochroman‐1‐ones and isobenzfuranones), imides, anhydrides and lactams in excellent yields (73–96%).