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Regioselective Benzylation of Diols and Polyols by Catalytic Amounts of an Organotin Reagent
Author(s) -
Xu Hengfu,
Lu Yuchao,
Zhou Yixuan,
Ren Bo,
Pei Yuxin,
Dong Hai,
Pei Zhichao
Publication year - 2014
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201301152
Subject(s) - chemistry , regioselectivity , reagent , catalysis , diol , vicinal , organic chemistry , bromide
An efficient one‐pot method for the selective benzylation of diols and polyols using 0.1 equiv. of organotin reagents and tetrabutylammonium bromide as catalyst has been developed. The diols and polyols containing a cis ‐vicinal diol were regioselectively benzylated in 70–94% isolated yields. A catalytic reaction mechanism was also proposed.