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An Efficient Rhodium/Oxygen Catalytic System for Oxidative Heck Reaction of Indoles and Alkenes via CH Functionalization
Author(s) -
Yang Lei,
Zhang Guoying,
Huang Hanmin
Publication year - 2014
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201301107
Subject(s) - rhodium , chemistry , catalysis , surface modification , oxygen , heck reaction , molecular oxygen , combinatorial chemistry , organic chemistry , oxidative phosphorylation , palladium , biochemistry
A rhodium(III)‐catalyzed direct selective C‐2 alkenylation reaction of indoles with alkenes has been developed with molecular oxygen as the sole oxidant. The rhodium/oxygen catalytic system is applicable to a broad range of indoles and alkenes, which provides a novel access to various C‐2 alkenylated indoles and pyrroles.