H‐Phosphonate‐Mediated Amination of Quinoline  N ‐Oxides with Tertiary Amines: A Mild and Metal‐Free Synthesis of 2‐Dialkylaminoquinolines | Zendy

Chen Xiaolan | Zendy; Li Xu | Zendy; Qu Zhibo | Zendy; Ke Diandian | Zendy; Qu Lingbo | Zendy; Duan Likun | Zendy; Mai Wenpeng | Zendy; Yuan Jinwei | Zendy; Chen Jianyu | Zendy; Zhao Yufen | Zendy

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H‐Phosphonate‐Mediated Amination of Quinoline N ‐Oxides with Tertiary Amines: A Mild and Metal‐Free Synthesis of 2‐Dialkylaminoquinolines

Author(s) -

Chen Xiaolan,

Li Xu,

Qu Zhibo,

Ke Diandian,

Qu Lingbo,

Duan Likun,

Mai Wenpeng,

Yuan Jinwei,

Chen Jianyu,

Zhao Yufen

Publication year - 2014

Publication title -

advanced synthesis and catalysis

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.541

H-Index - 155

eISSN - 1615-4169

pISSN - 1615-4150

DOI - 10.1002/adsc.201301065

Subject(s) - chemistry , phosphonate , quinoline , amination , reductive amination , carbon tetrachloride , metal , combinatorial chemistry , organic chemistry , polymer chemistry , catalysis

A synthetic strategy has been developed for the synthesis of 2‐dialkylaminoquinolines from easily available quinoline N ‐oxides, tertiary amines, diisopropyl H‐phosphonate and carbon tetrachloride (CCl 4 ) in one pot under metal‐free conditions at room temperature.

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