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Catalytic Asymmetric Synthesis of Chiral Benzofuranones
Author(s) -
Li Yao,
Li Xin,
Cheng JinPei
Publication year - 2014
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201301038
Subject(s) - chemistry , enantioselective synthesis , catalysis , chirality (physics) , structural motif , stereochemistry , combinatorial chemistry , nanotechnology , organic chemistry , chiral symmetry , biochemistry , physics , materials science , quantum mechanics , nambu–jona lasinio model , quark
The chiral benzofuranone structural motif is a prominent feature in many natural products, which exhibit a broad range of biological and pharmaceutical activities. In the past few years, a survey of chiral benzofuranone derivatives based on asymmetric catalysis reveals an increasing number of papers, which reflects the latest achievements to facilitate the synthesis of sufficient quantities of related compounds as potential medicinal agents and biological probes. Recent advances in this area are summarized and classified according to the structure of the starting substrate.