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Laccase and Laccase‐Mediated Systems in the Synthesis of Organic Compounds
Author(s) -
Mogharabi Mehdi,
Faramarzi Mohammad Ali
Publication year - 2014
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201300960
Subject(s) - laccase , chemistry , biocatalysis , oxidizing agent , amination , organic synthesis , multicopper oxidase , green chemistry , organic chemistry , redox , combinatorial chemistry , polymerization , biochemical engineering , catalysis , enzyme , reaction mechanism , polymer , engineering
Laccase, a blue multicopper oxidase, has recently received considerable attention because of its usefulness in oxidizing phenolic and non‐phenolic compounds, as well as its suitability for organic synthesis, environmental pollutant treatment, and other biotechnological applications. This review covers recent studies on the structural properties, occurrence, reaction mechnisms, redox mediators of laccases and their application in organic synthesis procedures, such as dimerization, polymerization, oxidation, and amination. We also present a brief discussion on laccase activity in non‐aqueous media. Given that the development of green protocols for the synthesis of pure compounds is one of the main goals of sustainable chemistry, the exploitation of laccases is expected to remain one of the most popular directions in future biocatalysis research.