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Flow Synthesis of Substituted γ‐Lactones by Consecutive Photocatalytic/Reductive Reactions
Author(s) -
Fagi Maurizio,
Bonassi Filippo,
Palmieri Alessandro,
Protti Stefano,
Ravelli Davide,
Ballini Roberto
Publication year - 2014
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201300859
Subject(s) - chemistry , photocatalysis , service (business) , flow chemistry , world wide web , library science , information retrieval , combinatorial chemistry , organic chemistry , computer science , catalysis , business , marketing
Various substituted -lactones were easily prepared under flow conditions by photocatalytic addition of aldehydes onto unsaturated esters followed by reduction of the resulting -keto esters with sodium borohydride (NaBH4); The -hydroxy esters obtained easily cyclized to give the desired heterocycles in good yield
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